Clinical studies
Academic studies
Academic studiesStudy design: Prospective, monocentric, randomised clinical trial
The objective of this study is to determine whether dexamethasone prolongs the duration of the analgaesic effect in a penile block, as it does in a caudal block, in circumcisions.
Phase: Phase 4 study
Principle investigator: Dr Joris Goossens
Research Centre: Maria Middelares General Hospital
Study design: Multicentre double-blinded, randomised, controlled clinical trial
To research the effect of both chilled and conventional (classical) radiofrequency (RF) treatment on individuals who have chronic knee pain and for whom conservative treatments have failed. The effect of this treatment will be compared with a sham procedure in terms of knee pain, knee function, quality of life, mental health and overall health care. Patients suffering from chronic knee pain caused by osteoarthrosis or persistent pain after a total knee replacement placement are eligible to participate and will be followed up for approximately two years as part of this study.
Principle investigator: Dr Pieter Vander Cruyssen
Principal: East Limburg Hospital
Research Centre: Maria Middelares General Hospital
SQuaD 4 Anaesthesia will provide support for the practical implementation of this study and the data collection.
Study design: Prospective, observational, multicentre study
This study aims to investigate the outcomes of aortic valve replacement with the AVALUS pericardial biological heart valve. This heart valve is also frequently used at Maria Middelares General Hospital for aortic valve replacements. This study will examine how patients fare up to one year post surgery. This is an observational study, with no additional interventions or examinations.
Principle investigator: Dr Koen Cathenis
Principal: Leuven University Hospital, Cardiac Surgery Department
Research Centre: Maria Middelares General Hospital
Study design: Monocentric, randomised and controlled non-inferiority study
With this study, we aim to compare bounded fluid therapy, in which the administration of intravenous fluid is limited to a predetermined volume, with targeted fluid therapy, in which the administration of intravenous fluid is controlled based on a specific filling parameter determined by blood pressure. If necessary, additional assessment is initiated to increase blood pressure medication. This study helps us evaluate the impact of these fluid therapies on blood flow and swelling of the reconstructed breast.
Principle investigator: Dr Silvie Allaert
Research Centre: Maria Middelares General Hospital
Industrial studies
Industrial studiesStudy design: Randomised, placebo-controlled, double-blind, multi-centre and multi-national study
The aim of this study is to compare the efficacy and safety of trimodulin as an adjunct to standard treatment with placebo (combined with standard treatment) in adult hospitalised individuals with SCAP, who require invasive mechanical ventilation.
Sponsor: Biotest AG
Phase: Phase 3 study
Local principal investigator: Dr Jan Heerman