Clinical Research Centre

Clinical Research Centre

For medical oncology, the study coordinators are Stefanie Dias, Mieke Van Den Berghe, Annelies Verkest, Flore Ryckebusch, Flore Herman and Melissa Sucaet. Danielle Delombaerde works closely with the study team as a scientific researcher.

Danielle Delombaerde graduated in 2019 from the University of Ghent with a Master’s Degree in Pharmaceutical Care. She then worked as a deputy pharmacist in two pharmacies. Since September 2020, she has been working as a scientific researcher where she is conducting a doctoral research on predicting immunotherapy-related toxicities under the supervision of Prof Dr Vulsteke and Dr Croes.

Stefanie Dias graduated in 2008 with a Professional Bachelor's degree in Midwifery from the Artevelde University of Applied Sciences in Ghent. She then received her Master's Degree in Health care Management and Policy in 2010 from the University of Ghent. She worked for six years as a midwife at Maria Middelares General Hospital and, in 2017, transferred to the Clinical Study Department for Medical Oncology.

Flore Herman graduated in 2014 with a Professional Bachelor's Degree in Nursing from the Artevelde University of Applied Sciences in Ghent. In 2016, she received her Master's Degree in Nursing and Midwifery from the University of Ghent. She worked as a nurse at the Oncology/Haematology Department of the St Lucas General Hospital in Ghent and at the Gastro-oncology Department of Ghent University Hospital. In February 2021, she started in the medical oncology clinical trial department. She currently combines this with a job at Ghent University Hospital as an oncology researcher.

Thomas Hollevoet graduated in 2014 with a professional bachelor’s in nursing from the Catholic University of Applied Sciences in Leuven. He worked as an orthopaedic surgical nurse at Leuven University Hospital for seven years. In 2022, he obtained a master's degree in nursing and midwifery from the University of Leuven. He started on the medical oncology clinical trial department in early January 2023.

Flore Ryckebusch graduated in 2012 with a professional Bachelor's Degree in Nursing from the Catholic University College in Kortrijk. In 2016, she received her Master's Degree in Nursing and Midwifery from the University of Ghent. She worked for five years as a theatre nurse at Maria Middelares General Hospital and, in September 2020, transferred to the Clinical Study Department for Medical Oncology.

Melissa Sucaet graduated in 2015 with a professional bachelor's degree in Nursing from the Arteveld University of Applied Sciences in Ghent. She then began her employment with the Geriatrics Department at Maria Middelares General Hospital. She pursued the combined master's degree in Health Care Management and Policy, graduating from Ghent University in 2018. In 2018, she worked as the Head Nurse for the Oncology Department and, in 2020, she transferred to our hospital's mobile team. Since 2022, Melissa has been part of the Oncological Clinical Research Department.

Mieke Van Den Berghe graduated from the University of Antwerp in 2002 with her Master's Degree in Biomedical Sciences. She subsequently obtained another degree in Biology. She carried out clinical research for large pharmaceutical companies for twelve years. In November 2016, she joined our cancer centre as study coordinator for cancer drug development.

Annelies Verkest graduated in 2008 with her professional Bachelor's Degree in Midwifery from the Artevelde University of Applied Sciences in Ghent. In 2016, she received her Master's Degree in Nursing and Midwifery from the University of Ghent. She worked for eleven years as a nurse at Maria Middelares General Hospital and, in August 2019, transferred to the Clinical Research Department for Medical Oncology. As a study coordinator, she is the operational leader of the team.

Mieke Teirlynck graduated with a Bachelor of Office Management degree, majoring in medical management assistant from Ghent University in Applied Sciences in 2017. Since then, she has been working at the secretariat of the Integrated Cancer Centre in Ghent. From January 2023, she will also work for the Clinical Study Department for Medical Oncology in conjunction with her job with the secretariat.

The Medical Oncology Study Team is managed by:

Urology Studies

Urology Studies

Prostate tumours

  • CAPItello-280: A phase-III, double-blind, randomised and placebo-controlled study assessing the efficacy and safety of Capivasertib and Docetaxel versus placebo and Docetaxel as treatment for patients who have metastatic castration-resistant prostate cancer (mCRPC).

Bladder tumours

  • SUNRISE 3: A Phase III, Open-Label, Multi-Centre, Randomised Study Evaluating the Efficacy and Safety of TAR-200 in Combination with Cetrelimab or TAR-200 Alone Versus Intravesical Bacillus Calmette-Guérin (BCG) in Participants with BCG-naïve High-Risk Non-Muscle Invasive Bladder Cancer (HR-NMIBC)
  • RC48G001 A Phase 2 Multi-Cohort, Open-Label, Multi-Centre Clinical Study Evaluating the Efficacy and Safety of Disitamab Vedotin (RC48-ADC) Alone or in Combination with Pembrolizumab in Subjects with Locally-Advanced Unresectable or Metastatic Urothelial Carcinoma That Expresses HER2

Gynaecology Studies

Gynaecology Studies

Ovarium

  • MK-2870-005/ENGOT-en23 A Phase 3, Randomised, Active-controlled, Open-label, Multicentre Study to Compare the Efficacy and Safety of MK-2870 Monotherapy Versus Treatment of Physician's Choice in Participants With Endometrial Cancer Who Have Received Prior Platinum-based Chemotherapy and Immunotherapy

Other Studies

Other Studies
  • MK3475-587: A multi-centre, open-label, phase-III study to evaluate the long-term safety and efficacy in participants who are currently under treatment or in follow-up in studies that include Pembrolizumab.

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